Luetje Laboratory Publication Archive

Hsiao, B., Mihalak, K.B., Magleby, K.L., Luetje, C.W. (2008) Zinc potentiates neuronal nicotinic receptors by increasing burst duration. Journal of Neurophysiology, in press.

Menashe, I., Abaffy, T., Hasin, Y., Goshen, S., Yahalom, V., Luetje, C.W., Lancet, D. (2007) Genetic Elucidation of Human Hyperosmia to Isovaleric Acid. PLoS Biology 5: e284.

Wanner*, K.W., Nichols*, A.S., Walden, K.K.O., Brockmann, A., Luetje, C.W., Robertson, H.M. (2007) A honeybee odorant receptor for the queen substance 9-oxo-2-decenoic acid.  Proceedings of the National Academy of Sciences 104: 14383-14388. *equal contributions.

Abaffy, T., Malhotra, A., Luetje, C.W. (2007) The molecular basis for ligand specificity in a mouse olfactory receptor: A network of functionally important residues. Journal of Biological Chemistry 282: 1216-1224.

Shiembob, D.L., Roberts, R.L., Luetje, C.W., McIntosh, J.M. (2006) Determinants of alpha-conotoxin BuIA selectivity on the nicotinic acetylcholine receptor beta subunit. Biochemistry, 45:11200-11207.

Mihalak, K.B., Carroll, F.I., Luetje, C.W. (2006) Varenicline is a partial agonist at alpha4beta2 and a full agonist at alpha7 neuronal nicotinic receptors. Molecular Pharmacology, 70:801-805.

Abaffy, T., Matsunami, H., Luetje, C.W. (2006) Functional analysis of a mammalian odorant receptor subfamily. Journal of Neurochemistry 97: 1506-1518.

Hsiao, B., Mihalak, K.B., Repicky, S.E., Everhart, D., Mederos, A., Malhotra, A., Luetje, C.W. (2006) Determinants of zinc potentiation on the alpha4 subunit of neuronal nicotinic receptors. Molecular Pharmacology 69: 27-36.

Luetje, C.W. (2004) Getting past the asterisk: The subunit composition of presynaptic nicotinic receptors that modulate striatal dopamine release. Molecular Pharmacology 65: 1333-1335.

Everhart, D., Cartier, G.E., Malhotra, A., Gomes, A.V., McIntosh, J.M., and Luetje, C.W. (2004) Determinants of potency on α-conotoxin-MII, a peptide antagonist of neuronal nicotinic receptors. Biochemistry 43: 2732-2737.

Maddox FN, Valeyev AY, Poth K, Wood PM, Holohean AM, Davidoff RA, Hackman JC, and Luetje CW. (2004) GABAA receptor subunit mRNA expression in cultured embryonic and adult human dorsal root ganglion neurons. Developmental Brain Research 149: 143-151.

Burnstein, K.L. and Luetje, C.W. (2004) Hormone resistance: it's SMRT to fight repression. Endocrinology 145: 1525-1526.

Everhart, P., Reiller, E., Mirzoian, A., McIntosh, J.M., Malhotra, A. and Luetje, C.W. (2003) Identification of residues that confer α-conotoxin PnIA sensitivity on the α3 subunit of neuronal nicotinic acetylcholine receptors. Journal of Pharmacology and Experimental Therapeutics 306: 664-670.

Krajewski J.L., Luetje C.W. and Kramer R.H. (2003) Tyrosine phosphorylation of rod cyclic nucleotide-gated channels switches off Ca2+/calmodulin inhibition. Journal of Neuroscience 23: 10100-10106.

Molokanova, E., Krajewski, J.L., Satpaer, D., Luetje, C. and Kramer, R.H. (2003) Subunit contributions to phosphorylation dependent modulation of rod cyclic nucleotide-gated channels. Journal of Physiology 552.2: 345-356.

Avalos, M, Parker, M.J., Maddox, F.N., Carroll, F.I. and Luetje, C.W. (2002) Effects of pyridine ring substitutions on the affinity, efficacy and subtype selectivity of neuronal nicotinic receptor agonist epibatidine. Journal of Pharmacology and Experimental Therapeutics 302: 1246-1252.

Mirzoian, A. and Luetje, C.W. (2002) Modulation of neuronal nicotinic acetylcholine receptors by mercury. Journal of Pharmacology and Experimental Therapeutics, 302: 560-567.

Parker, M.J., Harvey, S.C. and Luetje, C.W. (2001). Determinants of agonist binding affinity on neuronal nicotinic receptor ß subunits. Journal of Pharmacology and Experimental Therapeutics 299: 385-391.

Hsiao, B., Dweck, D. and Luetje, C.W. (2001) Subunit dependent modulation of neuronal nicotinic receptors by zinc. Journal of Neuroscience 21: 1848-1856.

Molokanova, E., Maddox, F., Luetje, C.W. and Kramer, R.H. (1999) Activity-dependent modulation of rod photoreceptor cyclic nucleotide-gated channels mediated by phosphorylation of a specific tyrosine residue. Journal of Neuroscience 19:4786-4795.

Parker, M.J., Beck, A. and Luetje, C.W. (1998) Neuronal nicotinic beta2 and beta4 subunits confer large differences in agonist binding affinity. Molecular Pharmacology 54: 1132-1139.

Grant, G.A., Luetje, C.W., Summers, R. and Xu, X.L. (1998) Differential Roles for Disulfide Bonds in the Structural Integrity and Biological Activity of kappa-Bungarotoxin, a Neuronal Nicotinic Acetylcholine Receptor Antagonist. Biochemistry 37: 12166-12171.

Luetje, C.W., Maddox, F.N. and Harvey, S.C. (1998) Glycosylation within the cys-loop and six residues near conserved cys192/cys193 are determinants of neuronal bungarotoxin sensitivity on the neuronal nicotinic receptor alpha3 subunit. Molecular Pharmacology 53: 1112-1119.

Kaiser, S.A., Soliakov., L., Harvey, S.C., Luetje, C.W. and Wonnacott, S. (1998) Differential inhibition by a-conotoxin-MII of the nicotinic stimulation of [³H]dopamine release from rat striatal synaptosomes and slices. Journal of Neurochemistry, 70: 1069-1076.

Harvey, S.C., McIntosh, J.M., Cartier, G.E., Maddox, F.N., and Luetje, C.W. (1997) Determinants of specificity for a-conotoxin MII on a3b2 neuronal nicotinic receptors.  Molecular Pharmacology, 51: 336-342.

Poth, K., Nutter, T., Cuevas, J., Parker, M.J., Adams, D.J. and Luetje, C.W. (1997) Heterogeneity of nicotinic receptor class and subunit mRNA expression among individual parasympathetic neurons from rat intracardiac ganglia. Journal of Neuroscience 17: 586-596.

Harvey, S.C., Maddox, F.N. and Luetje, C.W. (1996) Multiple determinants of dihydro-b-erythroidine sensitivity on rat neuronal nicotinic receptor a subunits.  Journal of Neurochemistry, 67: 1953-1959.

Harvey, S.C. and Luetje, C.W. (1996) Determinants of competitive antagonist sensitivity on neuronal nicotinic receptor beta subunits.  Journal of Neuroscience, 16: 3798-3806.